laboratoire de physique statistique
 
 
laboratoire de physique statistique

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ANNUAL REVIEW OF MATERIALS RESEARCH 


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2007
Single-molecule micromanipulation techniques - Neuman, K. C. and Lionnet, T. and Allemand, J.-F
ANNUAL REVIEW OF MATERIALS RESEARCH 3733-67 (2007)

Abstract : Single-molecule micrornanipulation techniques traditionally have been developed for biophysical applications, but they are being increasingly employed in materials science applications such as theology and polymer dynamics. Continuing developments and improvements in single-molecule manipulation techniques afford new opportunities in a broad range of fields. In this review we present an overview of current single-molecule manipulation techniques, with an emphasis on optical and magnetic tweezers, followed by a description of the elastic properties of single biopolymers. We then review die use of micrornanipulation techniques to locally probe material properties. To provide some insight into biophysical questions addressed by these techniques, we describe two applications, which further serve to illustrate the power and versatility of single-molecule micromanipulation techniques. We conclude with a brief discussion of emerging applications and techniques.