laboratoire de physique statistique
 
 
laboratoire de physique statistique

Publications

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JOURNAL OF APPLIED PHYSICS 


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P U B L I C A T I O N S



 
2011
Single molecule actuation and detection on a lab-on-a-chip magnetoresistive platform - Chaves, R. C. and Bensimon, D. and Freitas, P. P.
JOURNAL OF APPLIED PHYSICS 109 (2011)

Abstract : On-chip magnetic tweezers based on current loops were integrated with magnetoresistive sensors. Magnetic forces up to 1.0 +/- 0.3 pN are produced to actuate on DNA anchored to the surface of a flow cell and labeled with micrometer-sized magnetic beads. The levitation of the beads stretches the immobilized DNA. The relative position of the magnetic beads is monitored using spin-valve sensors. A bead vertical displacement resolution of 60 nm is derived for DNA molecular motor activity in a tweezer steady current regime. (C) 2011 American Institute of Physics. [doi:10.1063/1.3560853]