laboratoire de physique statistique
 
 
laboratoire de physique statistique

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JOURNAL OF NEUROSCIENCE METHODS 


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P U B L I C A T I O N S



 
2010
Automated imaging of neuronal activity in freely behaving Caenorhabditis elegans - Ben Arous, Juliette and Tanizawa, Yoshinori and Rabinowitch, Ithai and Chatenay, Didier and Schafer, William R.
JOURNAL OF NEUROSCIENCE METHODS 187229-234 (2010)

Abstract : In order to understand how neuronal circuits control locomotory patterns it is necessary to record neuronal activity of freely behaving animals. Here, using a new automated system for simultaneous recording of behavior and neuronal activity in freely moving Caenorhabditis elegans on standard agar plates, we show that spontaneous reversals from forward to backward locomotion reflect precisely the activity of the AVA command interneurons. We also witness spontaneous activity transients in the PLM sensory neurons during free behavior of the worm in standard conditions. We show that these activity transients are coupled to short spontaneous forward accelerations of the worm. (C) 2010 Elsevier B.V. All rights reserved.